Sarah C. Lowery

This paper maps mucin glycoforms in tumors using on-tissue digestion and mass spectrometry, revealing distinct glycosylation patterns in colorectal mucinous adenocarcinomas.

This study shows that loss of NgBR/cis-PTase function in the liver leads to fatty liver disease that progresses to hepatocellular carcinoma with 100% penetrance, and DGAT2 inhibition prevents this progression.

The paper introduces BOCTAG, a method to label glycoproteins in specific cell types within mixed cultures, enabling analysis of cell-specific glycosylation.