Ashish Kumar Sharma

This study shows PCSK9 inhibitors reduce AAA growth by enhancing macrophage efferocytosis through MerTK-dependent mechanisms and altering lipid metabolism in the aortic wall.

This study shows that inhibiting ferroptosis with liproxstatin-1 reduces AAA formation by decreasing inflammation and aortic remodeling in mice.

This study shows that BMP9 therapy reduces primary graft dysfunction after lung transplantation by improving endothelial function and reducing inflammation.

This study examines temporal changes in extracellular vesicle (EV) protein cargo in burn-injury patients and mice, showing distinct immune reprogramming effects at early and late post-injury stages.

This study shows that LxA4/FPR2 signaling reduces ferroptosis in alveolar epithelial cells via NRF2 activation, protecting against lung ischemia-reperfusion injury.

This study shows RvD2/GPR18 signaling enhances M-MDSC function to reduce AAA formation by suppressing inflammation and vascular remodeling.

This study shows that MerTK-dependent efferocytosis by monocytic-MDSCs reduces post-lung transplant ischemia-reperfusion injury.

This study shows that common TMEM173 alleles HAQ and AQ reduce inflammation in SAVI mice by preventing CD4 T cell depletion and restoring T-regs.