Shuliang Deng

This study identifies a PTER inhibitor that reduces food intake and body weight in mice, linking PTER function to obesity treatment.

This study identifies Lac-Phe as a mediator of metformin's anti-obesity effects through experiments in mice and human cohorts.

The paper develops genetic scores for 17,227 molecular traits using multi-omic data from INTERVAL and validates them across ancestries, demonstrating their utility in pathway analysis and disease association discovery.

The paper shows that AVPR1A in the amygdala mediates female susceptibility to chronic social isolation stress, with sex-specific effects mediated by AVP and estrogen receptor alpha.