Connie K. P. Tam

This study identifies FDA-approved compounds that inhibit ExoU, a virulence factor in Pseudomonas aeruginosa, and shows their efficacy in reducing corneal infection severity in multiple models.

This study shows that K6a restricts secretory autophagy of proinflammatory cytokines by interacting with Sec16A, reducing cytokine secretion in corneal epithelial cells.

This study shows that keratin 6a suppresses TLR-triggered inflammation in corneal epithelial cells by modulating ELKS/IKKε-dependent NF-κB activation, preventing excessive cytokine and chemokine production.