Author

Darel Martinez Bedoya

University of GenevaORCID 0000-0002-1603-5801Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Denis MiglioriniiD· 2 shared Suzel DavantureiD· 2 shared Valérie DutoitiD· 2 shared Alice MachadoiD· 1 shared Audrey Mansuet‐LupoiD· 1 shared Aurélie Thomas· 1 shared Barbara BurroniiD· 1 shared Berta MarzaliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Denis MiglioriniORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 28, 2026

Safety profiling of CAR-T cells using an organotypic human tissue platform

Alice Machado, Gary Birsen, Irena Rajnpreht…·Emmanuel Donnadieu

This paper develops an organotypic human tissue platform to assess CAR-T cell toxicity and shows it can predict tissue-specific toxicity profiles and identify factors influencing off-tumor effects.

DOI 10.64898/2026.07.25.740527

humanexperimental assay

𝕏 PostBluesky

ImmunologyCancer Immunology ResearchPeer-reviewedSep 13, 2024

PTPRZ1-targeting RNA CAR-T cells exert antigen-specific and bystander antitumor activity in glioblastoma

Darel Martinez Bedoya, Eliana Marinari, Suzel Davanture…·Denis Migliorini

This study develops and validates anti-PTPRZ1 RNA CAR-T cells for glioblastoma treatment, showing antigen-specific and bystander antitumor activity in preclinical models.

12 citations

humanscRNA-seq

𝕏 PostBluesky