Dan Li

Novel conserved RNA structural motifs regulate genome cyclization of yellow fever virus

This study identifies a conserved RNA tertiary motif in yellow fever virus that regulates genome cyclization through interactions with the 3'-small hairpin.

Impaired astrocytic Cx43 syncytial network in lateral habenula affects synaptic connectivity and drives adolescent stress-induced depression

This study identifies impaired astrocytic Cx43 syncytial networks in the lateral habenula as a driver of adolescent stress-induced depression through disrupted synaptic connectivity and neuronal function.

Single-Cell Translation and Apoptosis Profiling to Define Human CD34⁺ Cell Response to Specific Factors

The paper develops a flow cytometry protocol to measure single-cell protein synthesis and apoptosis in human CD34+ cells, revealing distinct functional profiles of small molecules in hematopoietic expansion.

Engineering Functionality-Optimized Fully Human B7-H3 CAR T Cells for Enhanced Solid Tumor Therapy

This study develops fully human B7-H3 CAR T cells using phage display, showing improved antitumor activity and reduced immune response in xenograft models.

Allogeneic CRISPR-Engineered CAR-T Cells Drive Potent Antitumor Activity in Solid Tumors

This study develops allogeneic CRISPR-engineered CAR-T cells targeting GPC2 and GPC3, showing potent antitumor activity in solid tumors with repeated dosing and no toxicity.

p300/CBP-Driven Acetylation Stabilizes PARP7 to Reinforce Negative Feedback on IFN-I Signaling

This study identifies p300/CBP-mediated acetylation of PARP7 as a mechanism to suppress IFN-I signaling in tumor cells, with implications for enhancing antitumor immunity.

Assessing the variations in breast/ovarian cancer risk for Chinese BRCA1/2 carriers

This study identifies Chinese-specific BRCA1/2 mutation-associated cancer risk regions and characterizes mutation penetrance in a Chinese population.

Neural Encoding for Human Visual Cortex with Deep Neural Networks Learning "What" and "Where"

This paper introduces a deep neural network framework to learn 'what' and 'where' in human visual cortex encoding, achieving better performance with fewer prior assumptions.

The reduced prevalence of macrolide resistance in Mycoplasma pneumoniae clinical isolates from pediatric patients in Beijing in 2016

The study reports macrolide resistance rates in Mycoplasma pneumoniae isolates from pediatric patients in Beijing, 2016, and identifies specific mutations associated with resistance.