Brahim Nait‐Oumesmar

This paper develops a humanized mouse model to study human oligodendrocyte maturation, remyelination, and drug efficacy in spinal cord injury.

This study shows that PSD-95 in oligodendrocytes is essential for activity-dependent myelin sheath growth through axon-oligodendrocyte connectivity in zebrafish.

This study shows that MCT2 is essential for oligodendrocyte myelin maintenance and axonal support, and its loss leads to myelin and axonal damage, which can be mitigated by a ketogenic diet.

This study identifies PAK1 and NF2/Merlin as regulators of actin dynamics in oligodendrocytes, showing their role in myelin formation and expansion.

This study identifies a conserved anti-inflammatory transcriptional cascade involving Gcm in flies and humans, showing its role in modulating inflammation across species.

The study finds reduced axon caliber in the associative striatum of Sapap3-KO mice, affecting signal conduction but not the sensorimotor striatum.