Shubhnita Singh

This study shows that progranulin deficiency worsens age-related vascular damage in mice, affecting endothelial function and vascular remodeling.

This study shows that progranulin (PGRN) is essential for vascular contractility by regulating mitochondrial function, mitophagy, and redox signaling in vascular smooth muscle cells.

This study shows that CCL5/CCR5 contributes to aldosterone-induced hypertension, vascular injury, and renal damage by promoting inflammation and oxidative stress.

This study shows ethanol-induced vascular dysfunction is mediated by AT1 receptor activation and mitochondrial dysfunction, which can be mitigated by losartan.