Rafael Menezes da Costa

This study shows that activating Beclin1 prevents aldosterone-induced cardiovascular damage by restoring autophagy, protecting vascular and cardiac function.

The paper investigates how TNF-α activates NOX5 to cause oxidative stress and umbilical artery dysfunction in preeclampsia.

This study shows that progranulin deficiency worsens age-related vascular damage in mice, affecting endothelial function and vascular remodeling.

This study shows that progranulin (PGRN) is essential for vascular contractility by regulating mitochondrial function, mitophagy, and redox signaling in vascular smooth muscle cells.

This study shows that CCL5/CCR5 contributes to aldosterone-induced hypertension, vascular injury, and renal damage by promoting inflammation and oxidative stress.