Randall McNally

This study characterizes the structural dynamics of recombinant vaults, showing that cargo loading stabilizes their conformation for high-payload cytokine delivery in cancer therapy.

This study encapsulates AAVs into protein vault nanoparticles to bypass neutralizing antibodies, enabling effective gene therapy despite preexisting immunity.

This paper develops an ingestible capsule that detects short-lived inflammatory biomarkers in the GI tract using genetically engineered probiotic biosensors and wireless readout technology.