Chia-Ni Tsai

This study identifies a structural trade-off in type IV pili that balances mechanical resilience and supramolecular adaptability using cryo-EM, simulations, and experimental validation.

This study shows that Pseudomonas aeruginosa uses motility to enhance phagocytosis by macrophages, while reduced motility in chronic infections helps evade engulfment, and T3SS activity enables acute immune evasion.