Harriet E. Allan

This study shows that hepatic xanthine oxidoreductase (XOR) sustains antithrombotic nitric oxide signaling through the nitrate-nitrite-NO pathway, and dietary nitrate can restore this signaling when endothelial NO is deficient.

This study shows trauma and hemorrhagic shock rapidly alter megakaryocyte activity and mobilization in mice within one hour.

This study shows that platelet extracellular vesicles containing mitochondria are internalized by neutrophils, altering their activation, adhesion, migration, and phagocytic capacity.

This paper uses multi-parameter flow cytometry and machine learning to characterize platelet sub-populations and their responses to agonists, achieving high accuracy in distinguishing platelet age and activation states.