Author

Bo Zhou

Salk Institute for Biological StudiesORCID 0000-0002-2360-5016Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Bo Zhou5 papers · China Agricultural University

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Dmitry LyumkisiD· 2 shared Gennavieve Gray· 2 shared Hye Jeong ShiniD· 2 shared Sriram AiyeriD· 2 shared Timothy S. StrutzenbergiD· 2 shared Zelin ShaniD· 2 shared A. N. EngelmaniD· 1 shared Avik BiswasiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBiochemistry

Dmitry LyumkisORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedOct 24, 2025

Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding

Tao Jing, Zelin Shan, Tung Dinh…·Dmitry Lyumkis

This study determines cryo-EM structures of HIV-1 integrase tetramers and intasome hexadecamers, revealing structural plasticity and functional roles in viral integration and RNA binding.

17 citationstop 3%

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BiophysicsbioRxivPreprintMar 10, 2025

Structural basis of context-dependent RORγt target gene activation on chromatin

Timothy S. Strutzenberg, Xiandu Li, Matthew D. Mann…·Dmitry Lyumkis

This study identifies how RORγt mutations affect gene activation by altering chromatin binding modes, explaining context-dependent autoimmunity and host defense outcomes.

DOI 10.1101/2025.03.10.642251

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