Lianping Xing

This study identifies Efhd1+ telocytes in the synovial lymphatic system and shows their role in lymphatic drainage and protection against inflammatory-erosive arthritis.

This paper uses lightsheet microscopy to study the lymphatic network in mouse knee joints, finding that post-traumatic OA leads to shorter, smaller branches with more total branching points.

This study identifies PDGFRβ as a target of proteasome inhibitors in aged mice, showing that its degradation impairs fracture repair and that combined PDGF-BB and proteasome inhibitor treatment improves repair.

This study shows senescent cells impair fracture repair in aged mice by increasing ubiquitination of PDGFRβ via TGFβ, suggesting a new therapeutic target.