Sharvani Mahadevaraju

The paper investigates how somatic Transformer and sex chromosome karyotype pathways regulate gene expression during Drosophila gonad development, showing their combined and exclusive effects on germ cell development.

The paper provides single nucleus and single cell RNA-seq data from Drosophila testes to study spermatogenesis, identifying rare cell types and developmental transitions.

The paper creates a single-cell transcriptomic atlas of the adult fruit fly, identifying over 250 cell types and analyzing gene signatures and sexual dimorphism across tissues.

The paper shows that X and 4th chromosomes are inactivated while Y chromosomes are active in Drosophila primary spermatocytes using single-cell RNA-Seq.