Author
Junichi Okada
Albert Einstein College of MedicineORCID 0000-0002-2860-5672Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links5 papers
Recent·Most cited
- Molecular BiologyNature MetabolismPeer-reviewed
Spatial hepatocyte plasticity of gluconeogenesis during the metabolic transitions between fed, fasted and starvation states
Junichi Okada, Austin Landgraf, Alus M. Xiaoli…·Jeffrey E. Pessin
The paper shows that gluconeogenic gene expression and activity in liver hepatocytes change spatially and temporally during feeding, fasting, and starvation states.
- BioinformaticsbioRxivPreprint
Widespread discordance between mRNA expression, protein abundance and de novo lipogenesis activity in hepatocytes during the fed-starvation transition
Austin Landgraf, Junichi Okada, Maxwell Horton…·Kosaku Shinoda
The paper examines mRNA, protein, and lipogenesis activity in hepatocytes during feeding and starvation, finding widespread discordance between mRNA and protein levels, especially in sex-biased genes and lipogenic pathways.
7 citations - NeuroscienceNature CommunicationsPeer-reviewed
Liver-innervating vagal sensory neurons play an indispensable role in the development of hepatic steatosis and anxiety-like behavior in mice fed a high-fat diet.
Jiyeon Hwang, Sangbhin Lee, Junichi Okada…·Young‐Hwan Jo
This study shows that liver-innervating vagal sensory neurons contribute to hepatic steatosis and anxiety-like behavior in mice on a high-fat diet, and their removal prevents obesity and improves metabolic outcomes.
42 citationstop 1% - PhysiologyPLoS BiologyPeer-reviewed
The development of hepatic steatosis depends on the presence of liver-innervating parasympathetic cholinergic neurons in mice fed a high-fat diet.
Jiyeon Hwang, Junichi Okada, Liu Li…·Young‐Hwan Jo
This study shows that parasympathetic cholinergic neurons innervating the liver prevent hepatic steatosis in mice on a high-fat diet by promoting browning of white adipose tissue and altering bile acid metabolism.
25 citationstop 4%