Author

Francesco Aulicino

University of BristolORCID 0000-0002-3097-3765Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Maria Pia CosmaiD· 2 shared Adrian JaniszewskiiD· 1 shared An ZwijseniD· 1 shared Anchel De Jaime-SogueroiD· 1 shared Annekatrien BoeliD· 1 shared Annick Francis· 1 shared Antonio Lo NigroiD· 1 shared Bernard K. van der VeeriD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersDevelopmental Biology

Maria Pia CosmaORCID

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3 papers

Recent·Most cited

Developmental BiologyNature CommunicationsPeer-reviewedMar 3, 2023

The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency

Paraskevi Athanasouli, Martina Balli, Anchel De Jaime-Soguero…·Frederic Lluı́s

This study shows that Wnt/TCF7L1 repression promotes primitive endoderm differentiation in mESCs by inhibiting naive and formative pluripotency factors.

31 citations

mousebulk RNA-seq

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Synthetic BiologyNucleic Acids ResearchPeer-reviewedJul 8, 2022

Baculovirus-vectored precision delivery of large DNA cargoes in human genomes

Francesco Aulicino, Martin Pelosse, Christine Toelzer…·Imre Berger

This paper develops a baculovirus-based system for delivering large DNA cargoes for CRISPR-based genome editing in human cells, achieving up to 30% correct interventions.

42 citations

humanCRISPR screen

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Synthetic BiologyNature CommunicationsPeer-reviewedOct 2, 2019

A tunable dual-input system for ‘on-demand’ dynamic gene expression regulation

Elisa Pedone, Lorena Postiglione, Francesco Aulicino…·Lucia Marucci

The paper develops a dual-input system to dynamically regulate gene expression and protein stability in mouse embryonic stem cells, enabling precise control of protein levels and faster response times.

51 citations

mouseexperimental assay

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