Sibylle von Vietinghoff

This study identifies renal mononuclear phagocytes as an intracellular reservoir for UPEC in pyelonephritis, showing that complement receptor-mediated entry promotes bacterial persistence and limits β-lactam efficacy.

The paper integrates kidney and urine proteomics with peptidomics and machine learning to identify encrypted antimicrobial peptides as functional effectors in human pyelonephritis.

This study identifies lactate as a metabolic driver of CD163+ macrophage polarization in human pyelonephritis, linking lactate metabolism to immune dysfunction.

This study identifies proteomic adaptations in human pyelonephritis, revealing elevated antimicrobial peptides and their potential protective role against systemic inflammation.

This study shows that dapagliflozin reduces peritoneal fibrosis and improves ultrafiltration in a mouse model of high-glucose peritoneal dialysis.