Author
Icahn School of Medicine at Mount SinaiORCID 0000-0002-3292-1635Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Abishek Balachandra Vaidya, Étienne Humblin, Nataliya Prokhnevska…·Alice Oliffson Kamphorst
This study shows that B cells support tumor-specific CD4 T cells to enhance PD-1 blockade efficacy, but antibody secretion is not necessary for long-term survival.
Raphaël Mattiuz, Jesse Boumelha, Emmanouil Aerakis…·Miriam Mérad
This study identifies the role of mature dendritic cells type 1 in forming, maintaining, and functioning tertiary lymphoid structures in cancer.
Sammy Navarre, Maki Ishibashi, Achuth Nair…·Jalal Uddin Ahmed
This study shows dendritic cells enhance CAR T cell persistence in irradiated tumors by antigen-dressing and stimulating CAR T cells through chimeric receptors.
Samarth Hegde, Bruno Giotti, Brian Y. Soong…·Miriam Mérad
The paper identifies NRF2-driven myeloid progenitor dysregulation that sustains immunosuppressive macrophages in tumors, showing NRF2 inhibition reduces their survival and enhances antitumor immunity.
Pauline Hamon, Matthew D. Park, Jessica Le Bérichel…·Miriam Mérad
The paper identifies TREM2-expressing macrophages as predictors of response to PD-1 blockade in HCC patients using clinical and spatial transcriptomic data.
Emir Radkevich, Darwin D’souza, Raphaël Mattiuz…·Vladimir Roudko
The paper benchmarks deconvolution tools for spatial transcriptomic data and introduces a novel pipeline to analyze tissue microenvironment dynamics.
Meriem Belabed, Matthew D. Park, Cédric M. Blouin…·Miriam Mérad
This paper shows that AXL inhibits cholesterol mobilization in dendritic cells, which is necessary for their maturation and immunogenic response to cancer.