Author

Jingxuan Guo

Washington University in St. LouisORCID 0000-0002-3344-2839Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

David R. SchuftaniD· 1 shared Druv BhagavaniD· 1 shared Ghiska RamahditaiD· 1 shared Huanzhu JiangiD· 1 shared Jonathan D. MorenoiD· 1 shared Jonathan R. SilvaiD· 1 shared Lavanya AryaniD· 1 shared Nathaniel HuebschiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBioengineering

David R. SchuftanORCID

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1 paper

Recent·Most cited

BioengineeringiSciencePeer-reviewedMay 10, 2024

Mechanical Resistance to Micro-Heart Tissue Contractility unveils early Structural and Functional Pathology in iPSC Models of Hypertrophic Cardiomyopathy

Jingxuan Guo, Huanzhu Jiang, David R. Schuftan…·Nathaniel Huebsch

This study uses iPSC-derived heart tissue models to show that mechanical stress exacerbates HCM-linked MYBPC3 mutations, leading to structural and functional cardiac pathology.

19 citationstop 4%

humanexperimental assay

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