Xing Zeng

This study identifies CLSTN3B as a driver of MASLD by promoting LD biogenesis and altering lipid partitioning between LDs and mitochondria, leading to mitochondrial dysfunction and oxidative stress.

The paper identifies CEND1 as a regulator of activity-dependent glucose metabolism by facilitating mitochondrial ATP channeling to hexokinase I.

The paper identifies two specialized intrinsic cardiac neuron subtypes in mice that play distinct roles in maintaining cardiac homeostasis and stress resilience.

This study shows that CLSTN3B promotes lipid droplet maturation in hepatocytes and that its deletion reduces steatohepatitis in mice, with a positive correlation between CLSTN3B expression and MASLD severity in humans.

This study identifies CLSTN3B as a key protein for adipocyte lipid droplet maturation by facilitating ER-LD contacts, enhancing lipid storage and metabolic health.

This paper introduces a bi-parental graph strategy to assemble and analyze hybrid plant genomes, demonstrating its effectiveness in resolving structural variations and allele-specific gene expression.