Author
University of California, San FranciscoORCID 0000-0002-3667-8097Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Lorraine Nuniz, Julia H. Pham, Juliette Jacques…·Franklin W. Huang
This study identifies TM4SF1 as a tumor-associated antigen in biliary tract cancers and shows anti-TM4SF1 CAR-T cells inhibit tumor growth in vitro and in vivo.
Amrik S. Kang, H. A. Johnson, Nicole Lei…·Arun P. Wiita
This paper develops dual-antigen targeting CAR-T cells against CD70 and active integrin β2 to overcome AML antigen heterogeneity and reduce off-tumor toxicity.
Anju Wadhwa, Haley E. Johnson, Kondapa Naidu Bobba…·Robert R. Flavell
This study demonstrates promising preclinical efficacy of aITGB2-targeted radiotheranostics for selective imaging and therapy in AML.
Heiko Yang, Hanbing Song, Elizabeth Yip…·Franklin W. Huang
Single cell RNA sequencing of bladder cancer subtypes identified a CA125+ cell state linked to aggressive features and TM4SF1 as a therapeutic target.
Corynn Kasap, Adila Izgutdina, Bonell Patiño-Escobar…·Arun P. Wiita
Structure-optimized CD27-based CAR-T cells targeting CD70 show >80-fold improved expansion in vivo and offer a potential therapy for high-risk multiple myeloma patients.