Author

Asish Dasgupta

Queen's UniversityORCID 0000-0002-3670-1197Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Ashley Y MartiniD· 2 shared Jeffrey D. MewburniD· 2 shared Kuang‐Hueih Chen· 2 shared Rachel E. T. BentleyiD· 2 shared Stephen L. ArcheriD· 2 shared Benjamin P. OttiD· 1 shared Bernard ThébaudiD· 1 shared Charles C.T. HindmarchiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Ashley Y MartinORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 8, 2025

The Core Subunit NDUFS2 in Mitochondrial Electron Transport Chain Complex I is Critical to Oxygen Responsiveness of Human Ductus Arteriosus Smooth Muscle Cells

Rachel E. T. Bentley, Kimberly J. Dunham‐Snary, Ashley Y Martin…·Stephen L. Archer

This paper shows that NDUFS2 in mitochondrial Complex I is critical for oxygen responsiveness in human DASMCs, affecting calcium, cell shortening, and mROS without altering respiration.

DOI 10.1101/2025.07.08.663799

humanbulk RNA-seq

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Pharmacology & ToxicologyHypertensionPeer-reviewedAug 20, 2024

Efficacy of Drpitor1a, a Dynamin-Related Protein 1 inhibitor, in Pulmonary Arterial Hypertension

Danchen Wu, Ross D. Jansen‐van Vuuren, Asish Dasgupta…·Stephen L. Archer

This study evaluates Drpitor1a, a Drp1 inhibitor, showing efficacy in reducing PAH in female rats and human PASMCs without toxicity.

21 citationstop 3%

humanrat

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