Author

Danchen Wu

Queen's UniversityORCID 0000-0003-3901-5907Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Ashley Y MartiniD· 2 shared Ruaa Al‐QazaziiD· 2 shared Stephen L. ArcheriD· 2 shared Antonella Abi-Sleimen· 1 shared Asish DasguptaiD· 1 shared Charlie Théberge· 1 shared Elahe AlizadehiD· 1 shared François PotusiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Ashley Y MartinORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintOct 23, 2025

Levosimendan Ameliorates Adverse Pulmonary Vascular Remodeling in Group-2 Pulmonary Hypertension.

Antonella Abi-Sleimen, Ruaa Al‐Qazazi, Yann Grobs…·François Potus

This study develops preclinical models of Group-2 pulmonary hypertension and shows that levosimendan improves cardiac function and reduces pulmonary vascular inflammation and remodeling.

DOI 10.1101/2025.10.23.684000

mouseexperimental assay

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Pharmacology & ToxicologyHypertensionPeer-reviewedAug 20, 2024

Efficacy of Drpitor1a, a Dynamin-Related Protein 1 inhibitor, in Pulmonary Arterial Hypertension

Danchen Wu, Ross D. Jansen‐van Vuuren, Asish Dasgupta…·Stephen L. Archer

This study evaluates Drpitor1a, a Drp1 inhibitor, showing efficacy in reducing PAH in female rats and human PASMCs without toxicity.

21 citationstop 3%

humanrat

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