MicrobiologyPLoS PathogensPeer-reviewed
Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge
Michael W. Grunst, Hwi Min Gil, Andres G. Grandea…·David T. Evans
This study shows that potent antibody-dependent cellular cytotoxicity (ADCC) by a V2-specific antibody is insufficient to protect macaques against SIV challenge, but reduced viral loads were observed with a neutralization-sensitive SIV variant.
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