Vittoria Raffa

This paper presents a transfection-free method for delivering Cas9:gRNA ribonucleoprotein using gold nanoparticles, achieving effective gene editing in human melanoma cells.

This paper introduces a nano-switch using dCas9 and gold nanorods to enable spatiotemporal control of gene editing in zebrafish embryos through near-infrared laser activation.

This paper describes an optimized protocol for long-term maintenance of mouse spinal cord organotypic slices transplanted with human neural stem cells to test cell replacement therapies for spinal cord injury.

The paper demonstrates that nano-pulling enhances axon regeneration in dorsal root ganglia by stabilizing microtubules and activating local translation.

The paper shows that mechanical stimulation via magnetic nano-pulling accelerates neural precursor maturation into neurons and alters neuronal network organization.

This study shows that magnetic nano-pulling induces axonal cytoskeleton remodeling, enhancing outgrowth and synapse maturation through microtubule density increase and local translation promotion.