Isabel C. Poschke

This study compares T cell development in humanized mice with and without murine MHC, finding that busulfan conditioning in MHC-deficient mice promotes activated T cells while irradiation favors naive T cells.

This paper introduces an automated image-based cell sorting method that enriches activated T cells from blood with high throughput and label-free morphology-based classification.

The paper introduces optiPRM, a targeted LC-MS workflow that enhances sensitivity for detecting mutation-derived neoepitopes from limited tumor samples.