Diego Ezequiel Alvarez

The paper identifies antiviral resistance mutations in chikungunya virus envelope proteins that reveal a transient functional interaction between distal domains during fusion.

This study improves the potency of N1-methylpseudouridine-modified self-amplifying RNA by identifying mutations that enhance RNA synthesis and antigen expression.

The paper screens a drug-like compound library to identify new antivirals against Chikungunya Virus, finding four potential drug candidates.

This study shows that dengue virus uses non-optimal codons in both human and mosquito cells, enhancing its fitness and suggesting synonymous codon choice is critical in host-pathogen interactions.

This study investigates how mutations in the CHIKV E1 glycoprotein's fusion loop and hinge affect virus infectivity in different cell types and hosts by altering E1-E2 dynamics.