Sara A. Thannickal

This study identifies the M segment of La Crosse virus as a key determinant of cell-to-cell spread, virulence, and plaque size across different viral isolates.

This study shows that GM-CSF and M-CSF differentially regulate CHIKV infection and antiviral responses in human macrophages, with M-CSF promoting antiviral states.

The paper identifies antiviral resistance mutations in chikungunya virus envelope proteins that reveal a transient functional interaction between distal domains during fusion.

This study uses genomic reassortment to identify how different segments of La Crosse virus affect infection and pathogenesis in vitro and in vivo.

This study investigates how mutations in the CHIKV E1 glycoprotein's fusion loop and hinge affect virus infectivity in different cell types and hosts by altering E1-E2 dynamics.