Charles D. Cohen

This study identifies metabolic and redox pathway dysregulation in HIV-associated coronary endothelial dysfunction using proteomics and MRI.

This study uses spatial transcriptomics to show that myocarditis involves widespread molecular changes in cardiomyocytes, not just immune cell areas.

This study shows GSNOR deletion protects male cardiac function with age but may worsen female cardiac function by removing an age-related SNO imbalance.

This study uses single-cell multiomic analysis to identify transcriptional circuits driving non-ischemic cardiac fibrosis in mouse and human hearts, showing reversibility of fibrosis-related changes.

This study shows splenic follicular B cells worsen heart failure after MI by presenting cardiac antigens via MHC II, promoting adverse cardiac remodeling.

The paper identifies B cell gene expression and interactions in healthy and diseased human myocardium, finding disease-specific changes in DCM and ARVC.

This study uses single-nucleus RNA sequencing to analyze adipose tissue changes in a mouse model of type-2 diabetes, revealing altered cellular phenotypes and transcriptional circuits.