Theodore E. Ewachiw

This study identifies TDP-43 as essential for satellite cell maintenance and muscle repair by supporting stress response transcripts during quiescence-to-GAlert transition.

This study shows that TDP-43 is essential for building and maintaining sarcomeres, as its absence leads to muscle atrophy and disrupted sarcomere organization.

This study shows that SREBP pathway inhibition slows PDAC tumor growth by disrupting lipid homeostasis, suggesting SCAP as a therapeutic target.