Amol Bhandare

This study identifies Cx26 hemichannels as a CO2 sensor in serotonergic neurons that mediates hypercapnic arousal by enabling serotonin release.

The paper shows that CO2 produced in axons gates Cx32 hemichannels in Schwann cells, mediating neuron-to-glia signaling and affecting myelin conduction.

This study investigates changes in respiratory chemosensitivity in mice with chronic epilepsy, finding reduced adaptive responses to hypercapnia and shifts in neuronal response patterns over time.

The paper uses imaging to study neural activity in brainstem regions during CO2 exposure in mice, revealing distinct roles for RTN, Raphe, and pFL in respiratory chemosensitivity.

The paper shows that CO2-binding to Cx26 in glial cells of the medulla oblongata contributes significantly to ventilatory responses to CO2.