Author
GenentechORCID 0000-0002-5295-6165Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Cristiana C Santos, Nadine Schweizer, Fátima Cairrão…·Pedro Manuel Dias Neto Domingos
This study shows Fbxo42 promotes degradation of Ataxin-2 granules, enabling Xbp1 translation and triggering cell death during terminal UPR activation.
Iratxe Zuazo-Gaztelu, David A. Lawrence, Ioanna Oikonomidi…·Avi Ashkenazi
This study identifies a nonenzymatic role of IRE1 in cancer cell cycle progression and tumor growth, independent of its kinase-RNase activity.
Érika de Carvalho, Abdulbasit Amin, Richard LiIttle…·Colin Adrain
This study shows that the EMC3 subunit is critical for lipid droplet homeostasis in mice and Drosophila, with loss of EMC3 causing triglyceride storage defects and reduced FITM2 levels.