Cancer BiologyPLoS BiologyPeer-reviewed
A nonenzymatic dependency on inositol-requiring enzyme 1 controls cancer cell cycle progression and tumor growth
Iratxe Zuazo-Gaztelu, David A. Lawrence, Ioanna Oikonomidi…·Avi Ashkenazi
This study identifies a nonenzymatic role of IRE1 in cancer cell cycle progression and tumor growth, independent of its kinase-RNase activity.
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