Michael I. Shribak

The paper measures cellular forces for nuclear centration in C. elegans embryos using centrifugation and microscopy, finding forces increase linearly with distance and friction is reduced in microtubule mutants.

The paper uses OI-DIC imaging to show that a transient increase in depletion force, caused by macromolecular crowding, contributes to mitotic chromosome condensation in human cells.

The paper develops a combined microscope platform that integrates quantitative phase contrast and super-resolution fluorescence imaging for high-sensitivity visualization of sub-cellular structures and molecules in their cellular context.