Cuauhtemoc Ulises Gonzalez

This study identifies dysregulated autophagosome-mitochondria contacts in tauopathy, showing that restoring these contacts improves autophagy and reduces tau pathology.

This study shows memantine inhibits calcium-permeable AMPA receptors, revealing a new mechanism distinct from NMDA receptors and suggesting therapeutic potential for neurological disorders.

This study reveals how negative allosteric modulators inhibit AMPA receptors by disrupting glutamate binding and outcompeting positive modulators, offering insights for therapeutic design.

This study shows that increasing synaptic GluN2B levels in the amygdala can make strong fear memories modifiable through reconsolidation disruption.