Rajan R. Chaudhari

The paper reports cryo-EM structures of the ETB receptor bound to the lasso peptide RES-701-3, revealing its inverse agonist mechanism through hydrophobic interactions and conformational stabilization.

The paper develops a sequence-based chaos game representation combined with deep learning for peptide/protein classification, showing superior performance in hemolytic/non-hemolytic peptide and HIV protease mutant classification.

JavaDL predicts cancer drug responses using chemical features with a Java-based deep learning model, achieving high accuracy and robustness in big data analysis.