Sabrina Guichard

This study assesses α-α-subunit interactions of Nav1.5 in a heterologous expression system and finds that interactions depend on N-linked glycosylation and non-native disulfide bonds.

The paper introduces an all-optical Diamond Heater-Thermometer to enable precise thermal modulation of ion channels in living cells.

The paper identifies the binding site of small molecule inhibitors NBA and IBA in TRPM4 using cryo-EM and patch clamp experiments.

This study shows that Trpm4 knockout in mice increases cardiac inflammation and fibrosis after myocardial infarction without improving survival.