ImmunologybioRxivPreprint
PPa1 insufficiency drives lysosomal storage disease and inflammatory macrophage expansion in the bone marrow.
Magdalena G. Grzemska, Luming Chen, Jamie L. Russell…·Evan Nair‐Gill
DOI 10.64898/2026.03.16.712247
Author
Jianhui Wang
The University of Texas Southwestern Medical CenterORCID 0000-0002-6335-8355Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagActivity by Year
2020-2026 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 41 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 papers
Recent·Most cited
- BiophysicsbioRxivPreprint
Structural insights into the ubiquitin independent MIDN-proteasome pathway
Nagesh Peddada, Xue Yun Zhong, Yan Yin…·Bruce Beutler
This study reveals how MIDN enhances proteasome activity through cryo-EM structures showing its binding to proteasomes and substrates in two conformational states.
- ImmunologyEMBO ReportsPeer-reviewed
Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and anti-tumor immunity.
Jamie Russell, Luming Chen, Aijie Liu…·Evan Nair‐Gill
This study identifies Lrp10 as a negative regulator of CD8 T cell homeostasis and tumor resistance by suppressing IL7R levels and enhancing anti-tumor immunity.
5 citations - GeneticsbioRxivPreprint
Candidate Explorer: a tool for discovery, evaluation, and display of mutations causing significant immune phenotypes
Darui Xu, Stephen Lyon, Chun Hui Bu…·Bruce Beutler
Candidate Explorer identifies causative mutations for immune phenotypes by integrating multiple data features into a score, improving mutation-phenotype association verification in mice.
DOI 10.1101/2020.11.07.371914