Byron B. Au‐Yeung

This study identifies IL-6-like genes in jawless vertebrates and shows their role in inflammation through STAT5 signaling and SOCS gene regulation.

This study identifies the role of Nr4a family nuclear receptors in transcriptional control of T cell tolerance during thymic development, showing their necessity for negative selection and anergy-like programs in self-reactive T cells.

This study shows that the adipocyte niche impairs T-cell function by modulating cytoskeletal dynamics and reducing TCR-antigen forces in both mice and human T-cells.