Author
Wellcome Centre for Cell BiologyORCID 0000-0002-6736-9203Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Kumiko Samejima, Johan Harmen Gibcus, Sameer Abraham…·William C. Earnshaw
In DT40 cells, condensins displace extrusive cohesin, bypass cohesive cohesin and stall against each other while extruding ~1-3 kb/sec, yielding irregular helical chromatids of consecutive loops.
Pragya Parashara, Bethan Medina‐Pritchard, Maria Alba Abad…·A. Arockia Jeyaprakash
The paper identifies PLK1-mediated phosphorylation of Mis18 and Mis18BP1 as essential for activating the Mis18 complex to ensure CENP-A loading and centromere inheritance.
Sundar Ram Sankaranarayanan, Satya Dev Polisetty, Kuladeep Das…·Kaustuv Sanyal
The paper identifies a conserved arginine residue in the Dam1 complex subunit Dad2 that is essential for viability in yeast but less so in fungi with regional centromeres, suggesting functional plasticity in chromosome-microtubule coupling.