Callum Michael Zgierski-Johnston

This study examines age-related changes in cardiac Schwann cells, parasympathetic nerve fibers, and M2R expression in mice, finding reduced SC density, fewer parasympathetic fibers, and lower M2R expression in aged hearts, which correlates with increased arrhythmia risk.

The paper quantifies the 3D structure and distribution of fibroblasts and macrophages in healthy and cryo-ablated mouse hearts using fluorescent labeling and imaging.

This study identifies perivascular excitation tunnelling (PVET) as a novel mechanism causing reperfusion arrhythmias and shows that two-step reperfusion can prevent it in rabbit and pig hearts.