Jonas Dehairs

This study shows that inhibiting de novo lipogenesis and supplementing with PUFAs suppresses prostate cancer progression by inducing oxidative stress and cell death.

This study identifies a lipid-mediated signaling pathway driven by microglia that promotes glioblastoma invasion and shows that targeting this pathway can suppress tumor invasion.

LipidQMap is an open-source tool for processing quantitative mass spectrometry imaging lipidomics data, enabling accurate and reproducible spatial lipid quantification across MSI platforms.

This study identifies TamL as essential for outer membrane integrity in Bacteroidetes, showing its role in maintaining membrane stability and interacting with TamB.

This study identifies ELOVL6 as a therapeutic target in pancreatic cancer by showing its role in c-MYC-driven lipid metabolism and its impact on chemotherapy efficacy.

This study identifies cis-vaccenic acid as a critical oncogenic factor in prostate cancer, showing it rescues cell viability loss from SCD1 inhibition and promotes growth.

This study integrates proteomics, transcriptomics, and metabolomics data from IEM patients to identify perturbed protein complexes and pathways, highlighting mitochondrial oxidative phosphorylation and histone acetylation dysregulation.

This study identifies defective lipid metabolism in Schwann cells as a cause of CMT1A, showing altered lipid composition and membrane dynamics in mouse models and human iPSC-derived cells.

This study shows that cholesterol in extracellular vesicles from repair macrophages enhances remyelination by promoting oligodendrocyte precursor cell differentiation.