Author
National University of SingaporeORCID 0000-0002-6843-5372Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Xuetong Li, Ziyi Feng, Ajeena Ramanujan…·Carlos F. Ibáñez
This study shows that p75NTR internalization differs between hippocampal and cerebellar neurons, regulated by distinct signaling pathways involving RhoA and NF-kB.
Vanessa Lopes-Rodrigues, Samuel Agyei Nyantakyi, Xueqing Lun…·Carlos F. Ibáñez
This study identifies a small molecule that inhibits melanoma migration and metastasis by targeting the transmembrane domain of p75NTR, showing promise for cancer treatment.
Ajeena Ramanujan, Zhen Li, Zhi Lin, Carlos F. Ibáñez
The paper shows how ligand-directed competition between RIP2 and RhoGDI for p75NTR engagement determines axon growth and neuron survival.
Chenju Yi, Ket Yin Goh, Lik‐Wei Wong…·Carlos F. Ibáñez
The paper shows that inactive p75NTR variants reduce Alzheimer's neuropathology by decreasing APP internalization and amyloidogenic processing in 5xFAD mice.