Author

Donna L. Senger

University of CalgaryORCID 0000-0003-2403-3395Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Douglas J. MahoneyiD· 2 shared Franz J. ZempiD· 2 shared Ngoc Ha Dang· 2 shared A. Sorana MorrissyiD· 1 shared Aaron H. GillmoriD· 1 shared Ajeena RamanujaniD· 1 shared Alexander J. LazariD· 1 shared Aly O. AbdelkareemiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

Douglas J. MahoneyORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyEMBO Molecular MedicinePeer-reviewedSep 17, 2025

Impaired migration and metastatic spread of human melanoma by a novel small molecule targeting the transmembrane domain of death receptor p75NTR

Vanessa Lopes-Rodrigues, Samuel Agyei Nyantakyi, Xueqing Lun…·Carlos F. Ibáñez

This study identifies a small molecule that inhibits melanoma migration and metastasis by targeting the transmembrane domain of p75NTR, showing promise for cancer treatment.

7 citations

humanexperimental assay

𝕏 PostBluesky

Cancer BiologyGenome biologyPeer-reviewedOct 10, 2024

Spatiotemporal modeling reveals high-resolution invasion states in glioblastoma

Varsha Thoppey Manoharan, Aly O. Abdelkareem, Gurveer Gill…·A. Sorana Morrissy

The paper uses a novel computational workflow to analyze a spatiotemporally profiled GBM xenograft cohort, identifying 15 tumor cell programs related to invasion and their prognostic significance in GBM patients.

17 citations

mousebulk RNA-seq

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Cancer BiologyNature CommunicationsPeer-reviewedFeb 7, 2024

ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97

Amir Pozner, Li Li, Shiv Prakash Verma…·Kevin B. Jones

This study identifies VCP/p97 as an obligate co-factor of ASPSCR1-TFE3, showing it organizes enhancer loops to drive oncogenic transcription in ASPS and RCC.

16 citations

humanmouse

𝕏 PostBluesky