Gabriel Ortega

This paper engineers conformational switches using nanobodies that fold upon ligand binding, enabling customizable receptors and sensors for biomarkers and drugs.

This study investigates how halophilic proteins achieve stability in high salt environments by analyzing the trade-off between electrostatic interactions and thermodynamic stability.

This study thermodynamically stabilizes human frataxin using computational methods, improving its stability and resistance to proteolysis without compromising function.