Carolina Tropini

The paper engineers a gut bacterium to enhance osmotic resistance, enabling it to survive malabsorption in industrialized microbiomes.

The paper tracks lineage evolution and transmission of Bacteroides thetaiotaomicron across hosts and ecological scales using genomic barcoding and whole-genome sequencing.

The paper shows that cell death affects the relationship between DNA replication-based estimates and population size changes in bacteria.

The paper shows that microbial persistence under osmotic stress in Bacteroides thetaiotaomicron depends on both growth capacity and reduced cell loss.

This study shows how osmotic conditions influence co-evolution between E. coli and T4 phage, with different resistance mechanisms emerging under varying osmolalities.

The paper examines genetic diversity distribution in gut bacteria across different gut regions and finds it is uniform despite varying species composition.

This study shows that bowel preparation with PEG increases susceptibility to pathogens and exacerbates inflammation in mouse and in vitro models.

The paper expands genetic tools for Bacteroides thetaiotaomicron to create biosensors for detecting gut malabsorption through fluorescence-based environmental sensing.

This study correlates genetic expression and electrochemical activity in Bacillus subtilis biofilms, showing electrochemical activity is present in biofilm-forming cells but not in biofilm-deficient mutants.

This study investigates how early-life gut inflammation affects microbiome, endocrine, and behavioral outcomes, revealing sex-specific impacts on microbiota composition, hormone levels, and behavior.

PUPpy designs taxon-specific primers for substrain-level microbial detection and absolute quantification, outperforming 16S rRNA and shotgun sequencing in defined communities.