Katharine M. Ng

The paper engineers a gut bacterium to enhance osmotic resistance, enabling it to survive malabsorption in industrialized microbiomes.

The paper shows that microbial persistence under osmotic stress in Bacteroides thetaiotaomicron depends on both growth capacity and reduced cell loss.

This study shows that gut microbiome recovery after antibiotics is path-dependent, shaped by ecological and evolutionary dynamics including strain sweeps, genetic changes, and phage activity.

This study shows that bowel preparation with PEG increases susceptibility to pathogens and exacerbates inflammation in mouse and in vitro models.

This study investigates how early-life gut inflammation affects microbiome, endocrine, and behavioral outcomes, revealing sex-specific impacts on microbiota composition, hormone levels, and behavior.

PUPpy designs taxon-specific primers for substrain-level microbial detection and absolute quantification, outperforming 16S rRNA and shotgun sequencing in defined communities.

This study uses single-cell RNA-sequencing to analyze cell type-specific responses to young or aged blood in heterochronic parabiosis, identifying mitochondrial function as a key factor in rejuvenation.