Leila Mureşan

The paper examines tau aggregates in Alzheimer's disease synaptosomes, finding that small tau aggregates are associated with early synaptic pathology.

This study uses 3D super-resolution microscopy to analyze PSD95 nanoarchitecture in the mouse brain, revealing diffuse supercomplexes outside synapses and distinct subtypes within synapses.

This study uses live imaging to show mitotic errors and lineage plasticity in human embryos before implantation, revealing implications for aneuploidy mosaicism.

This study shows that substrate stiffness affects neuronal maturation by regulating Piezo1-mediated TTR activity, delaying synapse formation and electrical maturation.

The paper uses super-resolution microscopy to study histone modifications in Drosophila Y loops, revealing exclusivity of modifications at the chromatin cluster level and their association with transcriptional activity.

The paper investigates changes in CSL transcription complex behavior under Notch active conditions using single molecule microscopy, finding increased binding and exploratory behavior.

BigNeuron benchmarks automatic neuron reconstruction algorithms using gold standard annotations and image quality metrics, showing that consensus methods outperform individual algorithms.

The paper identifies a correlation between low Arc mRNA levels in specific locus coeruleus neurons and the development of compulsive polydipsic drinking in rats.

This study uses super-resolution microscopy to analyze the structure of transcriptionally active chromatin loops in Drosophila primary spermatocytes, revealing their organization into nucleosome clusters and RNA polymerase foci.

This study shows that zebrafish presomitic mesoderm elongates through compression and cell density increase, not posterior growth, and tail somites form without PCP signaling.

The paper shows MAVS polymers induced by dsRNA are smaller than 80 nm and require the transmembrane domain for mitochondrial remodeling and interferon signaling.

This paper demonstrates Single Molecule Light Field Microscopy (SMLFM) for extended depth-of-field super-resolution imaging by measuring disparity in point emitter localizations across multiple perspectives.

The paper uses live imaging to study cell movement during somite formation in chick embryos, revealing both random and directed motion in different regions.

The paper traces neuromesodermal progenitors in zebrafish embryos to show they contribute to spinal cord and mesoderm with distinct growth dynamics across species.