Aminopeptidase N is a receptor for hedgehog merbecoviruses
Min Jin, Victoria A. Jefferson, Zhe Zhao…·Michael C. Letko
This study identifies Aminopeptidase N as the receptor for hedgehog merbecoviruses and shows restricted cross-species receptor use.
Author
Washington State UniversityORCID 0000-0002-7640-2861Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
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Min Jin, Victoria A. Jefferson, Zhe Zhao…·Michael C. Letko
This study identifies Aminopeptidase N as the receptor for hedgehog merbecoviruses and shows restricted cross-species receptor use.
Alexander J. Brown, Anna C. Fagre, Julianna Gilson…·Stephanie N. Seifert
This study compares the susceptibility of Old World and New World bat cell lines to Zika virus, finding that Old World bat cells support viral replication and strong inflammatory responses.
Jarel Elgin Tolentino, Victoria A. Jefferson, Nicholas Catanzaro…·Kei Sato
This study identifies structural and phenotypic changes in the RBD loop2 region of HKU5r-CoVs as key factors enabling their emergence in mink and potential zoonotic transmission.
B. R. Ansil, Guang-Sheng Lei, Aaron J. Santos…·Daniel J. Becker
The paper identifies novel and previously known alphacoronaviruses in three bat species in Belize and finds phylogenetic similarity between bat CoVs and human 229E and NL63 coronaviruses.
Nicholas J. Catanzaro, Ziyan Wu, Chengcheng Fan…·Michael C. Letko
The paper identifies ACE2 as a receptor for HKU5 coronaviruses from Pipistrellus abramus bats and investigates receptor tropism across merbecovirus clades.
Victoria Gonzalez, Cierra Word, Nahomi Guerra-Pilaquinga…·Michael C. Letko
This study generates and characterizes bat cell lines from Carollia perspicillata to study viral susceptibility and innate immune responses, showing their utility for virological research.
Neeltje van Doremalen, Trenton Bushmaker, Robert J. Fischer…·Vincent Jacobus Munster
This study demonstrates limited MERS-CoV transmission via aerosol, fomite, and direct contact in a transgenic human DPP4 mouse model.